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Journal articles
Carbon nanotubes in macrophages: imaging and chemical analysis by X-ray fluorescence microscopy
Cyrill Bussy
1
Julien Cambedouzou
2
Sophie Lanone
3
Emilie Leccia
2
Vasile Heresanu
4
Mathieu Pinault
5
Martine Mayne-L'hermite
5
Nathalie Brun
2
Claudie Mory
2
Marine Cotte
6
Jean Doucet
2
Jorge Boczkowski
3
Pascale Launois
2
3
INSERM U955, équipe 4
LPS - Laboratoire de Physique des Solides, Nanomedicine laboratory, IMRB - Institut Mondor de Recherche Biomédicale
Cyrill Bussy 1
Author
Julien Cambedouzou 2
Author
Sophie Lanone 3
Author IdHAL : sophie-lanone ORCID : https://orcid.org/0000-0003-2509-8799
Emilie Leccia 2
Author
Vasile Heresanu 4
Author IdHAL : vasile-heresanu ResearcherId : http://www.researcherid.com/rid/B-8995-2019 ORCID : https://orcid.org/0000-0001-8267-7231
Mathieu Pinault 5
Author
Martine Mayne-L'hermite 5
Author
Nathalie Brun 2
Author
Pascale Launois 2
Author
2
LPS - Laboratoire de Physique des Solides (Bat. 510 91405 Orsay cedex - France)
- UP11 - Université Paris-Sud - Paris 11 (Bâtiment 300 - 91405 Orsay cedex - France)
- CNRS - Centre National de la Recherche Scientifique : UMR8502 (France)
3
INSERM U955, équipe 4 (United Kingdom)
- LPS - Laboratoire de Physique des Solides (Bat. 510 91405 Orsay cedex - France)
- UP11 - Université Paris-Sud - Paris 11 (Bâtiment 300 - 91405 Orsay cedex - France)
- CNRS - Centre National de la Recherche Scientifique : UMR8502 (France)
- Nanomedicine laboratory (London WC1N 1AX - United Kingdom)
- UCL - University College of London [London] (Gower Street, London WC1E 6BT - United Kingdom)
- Centre for Drug Delivery Research (France)
- UCL School of Pharmacy (France)
- IMRB - Institut Mondor de Recherche Biomédicale (8 rue du Général Sarrail 94010 Créteil - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U955 (101, rue de Tolbiac, 75013 Paris - France)
- IFR10 (France)
- UPEC UP12 - Université Paris-Est Créteil Val-de-Marne - Paris 12 : UMR955 (61 avenue du Général de Gaulle - 94010 Créteil cedex - France)
4
CINaM - Centre Interdisciplinaire de Nanoscience de Marseille (CINaM-CNRS Campus de Luminy Case 913 13288 Marseille Cedex 9 - France)
- AMU - Aix Marseille Université : UMR7325 (Aix-Marseille Université Jardins du Pharo 58 Boulevard Charles Livon 13284 Marseille cedex 7 - France)
- CNRS - Centre National de la Recherche Scientifique : UMR7325 (France)
5
SPAM - Service des Photons, Atomes et Molécules (Direction des Sciences de la Matière CEA Saclay, Bâtiment 522 F-91191 Gif-sur-Yvette - France)
- CEA - Commissariat à l'énergie atomique et aux énergies alternatives : DSM/IRAMIS (Centre de Saclay Centre de Grenoble Centre de Cadarache etc - France)
6
ESRF - European Synchrotron Radiation Facility (6 rue Jules Horowitz BP220 38043 GRENOBLE CEDEX - France)
Abstract : X-ray fluorescence microscopy (μXRF) is applied for the first time to study macrophages exposed to unpurified and purified single-walled (SW) and multiwalled (MW) carbon nanotubes (CNT). Investigating chemical elemental distributions allows one to (i) image nanotube localization within a cell and (ii) detect chemical modification of the cell after CNT internalization. An excess of calcium is detected for cells exposed to unpurified SWCNT and MWCNT and related toxicological assays are discussed.
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Journal articles
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https://hal.archives-ouvertes.fr/hal-02925956
Contributor : Pascale Launois <>
Submitted on : Monday, August 31, 2020 - 10:57:09 AM
Last modification on : Friday, March 5, 2021 - 3:05:36 PM
Long-term archiving on: : Tuesday, December 1, 2020 - 12:15:04 PM
Contributor : Pascale Launois <>
Submitted on : Monday, August 31, 2020 - 10:57:09 AM
Last modification on : Friday, March 5, 2021 - 3:05:36 PM
Long-term archiving on: : Tuesday, December 1, 2020 - 12:15:04 PM
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- HAL Id : hal-02925956, version 1
- DOI : 10.1021/nl800914m
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Citation
Cyrill Bussy, Julien Cambedouzou, Sophie Lanone, Emilie Leccia, Vasile Heresanu, et al.. Carbon nanotubes in macrophages: imaging and chemical analysis by X-ray fluorescence microscopy. Nano Letters, American Chemical Society, 2008, 8 (9), pp.2659-2663. ⟨10.1021/nl800914m⟩. ⟨hal-02925956⟩
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